Copyright: © 2025 by the authors. Licensee: Pirogov University.
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ORIGINAL RESEARCH

Antiviral activity of mRNAS encoding intracellular scFv antibodies against conserved influenza virus epitopes

Plotnikova MA , Oleynik VA , Klotchenko SA
About authors

Smorodintsev Research Institute of Influenza, St. Petersburg, Russia

Correspondence should be addressed: Sergey A. Klotchenko
Professora Popova, 15/17, Saint Petersburg, 197022, Russia; ur.liam@kitafsof

About paper

Funding: This study was supported by financially by the Russian Science Foundation, Agreement No. 24-25-00488: "Study of the antiviral potential of intracellular scFv antibodies against influenza virus" (supervisor — S.A. Klotchenko), https://rscf.ru/project/24-25-00488/

Author contribution: Plotnikova MA — design of structures, conducting experiments, registration and analysis of results, statistical processing, manuscript authoring and formatting; Oleynik VA — conducting experiments, registration of results; Klotchenko SA — study design, preparation and characterization of mRNA preparations, conducting experiments, registration and analysis of results, manuscript editing.

Received: 2025-11-27 Accepted: 2025-12-10 Published online: 2025-12-26
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