ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2026 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Construction and characterization of the attenuated recombinant influenza virus strains expressing human interleukin 1β
About authors
Smorodintsev Research Institute of Influenza, St. Petersburg, Russia
Correspondence should be addressed: Ekaterina A. Romanovskaya-Romanko
Professora Popova, 15/17, St. Petersburg, 197022, Russia; ur.xednay@akmormor
About paper
Funding: the study was supported by the Russian Science Foundation (project No. 25-25-00939).
Author contribution: Romanovskaya-Romanko EA — concept, testing, material processing, manuscript writing; Ozhereleva OO — literature review, constructing plasmids, testing, statistical data processing; Plotnikova MA — testing, statistical data processing; Altuhov AS — testing; Stukova MA — approval of the final version of the article.
Compliance with ethical standards: the study was approved by the Ethics Committee of the Smorodintsev Research Institute of Influenza of the Ministry of Health of the Russian Federation (protocol No. 07 dated April 23, 2026). Animals were kept under standard conditions in accordance with the Directive 2010/63/ЕС, federal guidelines, and the institutional policy of the Smorodintsev Research Institute of Influenza of the Ministry of Health of the Russian Federation.
Received: 2026-07-02
Accepted: 2026-07-28
Published online: 2026-08-17
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