Copyright: © 2026 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Integrative pharmacognostical profiling & in vitro antibacterial activity assessment of Murraya koenigii (L.) spreng

Kareem AT
About authors

Department of Pharmacognosy, College of Pharmacy, Thi-Qar University, Thi-Qar, Iraq

Correspondence should be addressed: Ashwaq T. Kareem
Thi-Qar University, Thi-Qar, Iraq; qi.ude.qtu@meerak.t.qawhsa

Received: 2026-07-18 Accepted: 2026-08-20 Published online: 2026-08-31
|
  1. El-Shiekh RA, et al. Anticholinesterases activity of Murraya koenigii (L.) Spreng. and Murraya paniculata (L.) Jacq. essential oils with GC/MS analysis and molecular docking. Natural Product Research. 2024; 38 (12): 2155–9.
  2. Aniqa A, Kaur S. Phytochemical screening of hydroethanolic Murraya koenigii Spreng leaves extract by spectroscopic methods. Journal of Drug Research in Ayurvedic Sciences. 2024; 9 (4): 273–85.
  3. Maheswari KU, Sankar S. In silico molecular docking of phytochemicals of Murraya koenigii against Streptococcus mutans. Cureus. 2024; 16 (2).
  4. Savitha G, Balamurugan S. Pharmacognostical and antibacterial evaluation of Murraya koenigii (L) Spreng. International Letters of Natural Sciences. 2014; 17.
  5. Nagappan T, Ramasamy P, Vairappan CS. Chemotaxonomical markers in essential oil of Murraya koenigii. Natural Product Communications. 2012; 7 (10): 1934578X1200701034.
  6. Verma RS, et al. Phytochemical diversity of Murraya koenigii (L.) Spreng. from western Himalaya. Chemistry & Biodiversity. 2013; 10 (4): 628–41.
  7. Patil N, et al. Pharmacognostical, Preliminary phytochemical screening and Antibacterial activity of methanol Extract of Murraya koenigii. PharmaTutor. 2019; 7 (2): 18–20.
  8. Rajendran MP, Pallaiyan BB, Selvaraj N. Chemical composition, antibacterial and antioxidant profile of essential oil from Murraya koenigii (L.) leaves. Avicenna journal of phytomedicine. 2014; 4 (3): 200.
  9. Chibueze IJ, Emenike I. Murraya koenigi — a boon in different patological conditions. Universal Journal of Pharmaceutical Research. 2016.
  10. Organization WH. Quality control methods for herbal materials. 2011: World Health Organization.
  11. Sindhu RK, Arora S. Phytochemical and Pharmacognostical Studies on Murraya koenigii (L) spreng. Roots. Drug Invention Today. 2015; 7 (1).
  12. Adebajo AC, et al. Evaluation of the Ethnomedical Claims of Murraya koenigii. Pharmaceutical Biology. 2005; 42 (8): 610–20.
  13. Kumar KT, Sundar PD. Evaluation of antibacterial, antifungal and anthelmintic activity of Murraya Koenigii spreng. 2011.
  14. Kaur S, et al. Chemopreventive activity of hydroethanolic Murraya koenigii leaves extract (HEMKLE) against chemically induced skin carcinogenesis in mice. International Journal for Vitamin and Nutrition Research. 2020.
  15. Handral HK, Pandith A, Shruthi S. A review on Murraya koenigii: multipotential medicinal plant. Asian J Pharm Clin Res. 2012; 5 (4): 5–14.
  16. Handral HK, Jha PK. Pharmacognostic and phytochemical studies on the leaves of Murraya koenigii (L) Spreng. Pharmacophore. 2010; 1 (3): 231–8.
  17. Meena S, et al. Transcriptomic insight into terpenoid and carbazole alkaloid biosynthesis, and functional characterization of two terpene synthases in curry tree (Murraya koenigii). Scientific Reports. 2017; 7 (1): 44126.
  18. Kashyap S, Rathod Y, Biswas S. Murraya koenigii methanolic extract inhibits bacterial growth and biofilm of Staphylococcus aureus and Enterococcus faecalis. Scientific Reports. 2025; 15 (1): 34056.
  19. Samanta SK, et al. Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine. Pharmacological research. 2018; 129: 227–36.
  20. Saadoon SJ, et al. Surgical site infection: The Physiological Changes & the Effect of Using Preoperative Antibiotic Prophylaxis in Orthopedic Surgeries. Bulletin of Pharmaceutical Sciences Assiut University. 2026.
  21. Patil R, Mandlik S, Mandlik D. Murraya koenigii (Curry Tree): A review of its phytochemistry, ethnomedicinal uses, and pharmacology with respect to molecular mechanisms. Current Traditional Medicine. 2024; 10 (5): 73–97.
  22. Nandan S, et al. Quantitative analysis of bioactive carbazole alkaloids in Murraya koenigii (L.) from six different climatic zones of India using UPLC/MS/MS and their principal component analysis. Chemistry & Biodiversity. 2021; 18 (12): e2100557.
  23. Mondal P, et al. Extract of Murraya koenigii selectively causes genomic instability by altering redox-status via targeting PI3K/AKT/Nrf2/caspase-3 signaling pathway in human non-small cell lung cancer. Phytomedicine. 2022; 104: 154272.
  24. Nadaf S, et al. Antiproliferative and caspase-mediated apoptosis inducing effects of Murraya koenigii seeds against cancer cells. South African Journal of Botany. 2020; 132: 328–37.
  25. Choudhury RP, Garg A. Variation in essential, trace and toxic elemental contents in Murraya koenigii–A spice and medicinal herb from different Indian states. Food Chemistry. 2007; 104 (4): 1454–63.
  26. Gahlawat DK, Jakhar S, Dahiya P. Murraya koenigii (L.) Spreng: an ethnobotanical, phytochemical and pharmacological review. Journal of Pharmacognosy and Phytochemistry. 2014; 3 (3): 109–19.
  27. Abdullah R, et al. Phytochemical and antimicrobial properties of different plants and in silico investigation of their bioactive compounds in wound healing and rheumatism. Saudi Journal of Biological Sciences. 2024; 31 (3): 103942.
  28. Cowan MM. Plant products as antimicrobial agents. Clinical microbiology reviews. 1999; 12 (4): 564–82.
  29. Franyoto, YD, A. Nurrochmad, and N. Fakhrudin, Murraya koenigii L. Spreng.: An updated review of chemical composition, pharmacological effects, and toxicity studies. Journal of Applied Pharmaceutical Science. 2024; 14 (6): 011–027.