Bulletin of RSMU

ISSN Print 2500–1094 ISSN Online 2542–1204

Bulletin of RSMU

BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

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Belonocosov DA, Lebedeva AYu, Gordeev IG

The role of inflammation in the development and progression of cardiovascular diseases has been studied for decades. However, the start of use of endovascular methods in the treatment of coronary heart disease changed the approach to the problem. Barotrauma of coronary arteries, subintimal haemorrhage, endothelial dysfunction, cellular and molecular mechanisms of inflammation are among the key factors affecting the neointima formation and occurrence of restenosis at the site of intervention. In this review there are considered the basics of pathophysiology of inflammation after percutaneous coronary interventions (PCI) as well as existing and researched approaches to the anti-inflammatory therapy in the group of patients with coronary heart disease.

Received: 2013-08-02

Published online: 2017-01-05

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VIEWS 4495

Skoroglyadov AV, Lyadova MV, Ratjev AP

iln the article the basic principles and methods of treatment of traumas of the musculoskeletal system in patients with mental disorders are defined. On the basis of concrete clinical data basic approaches to the treatment of traumas in these patients are demonstrated. Mistakes and complications in their treatment are specified.

Received: 2013-06-17

Published online: 2017-01-05

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VIEWS 4662

Lazishvili GD, Zatikyan VR, Shukyur-Zade ER, Kornaev AS, Akmataliev KI, Danilov MA

The article is devoted to the actual direction of modern orthopedics — surgical treatment of local cartilage and osteochondral defects of the knee joint. The first part of the article includes the analysis of the current situation on this problem in the national health care. There are suggested the ways of the implementation of modern biotechnology in the practice of medicine. The second part of the article presents the analysis of surgical treatment of 39 patients with full-thickness cartilage or osteochondral defects of the femoral condyles. All patients applied autologous matrix-induced chondrogenesis technology, based on tunneling subchondral bone and implanting collagen matrix. A high percentage of positive outcomes of such operations (in terms of up to 5 years) indicates undisputed promise of using biomaterials in the treatment of cartilage damage.

Received: 2013-06-17

Published online: 2017-01-05

DOI:

Comments 0

VIEWS 4665

Roth A, Venbrocks RA, Skoroglyadov AV, But-Gusaim AB, Sirotin IV, Pimenov AA

I The article describes the experience of application of minimally invasive access for hip replacement developed by surgeons at the Department of Orthopedic of F. Schiller University of Jena, Germany. The surgical technique in details was described. Efficiency of the method was proved by the analysis of the results of treatment of 33 patients.

Received: 2013-06-17

Published online: 2017-01-05

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VIEWS 4251

Skoroglyadov AV, Ivkov AV, Shneyderov MV

I The article is devoted to the intramedullary osteosynthesis of clavicle fractures with different clamps, including the use of an originally designed pin (utility patent No. 119227 from 20.08.2012), developed at the Department of Traumatology, Orthopaedics and Battle-Field Surgery of Pirogov Russian National Research Medical University. The design of this pin allows performing osteosynthesis including severe comminuted fractures. The results were regarded as good or excellent.

Received: 2013-06-17

Published online: 2017-01-05

DOI:

Comments 0

VIEWS 4344

Ratjev AP, Skoroglyadov AV, Korobushkin GV, Zhavoronkov EA, Lyadova MV

The purpose of this study was the development of an effective system of treatment for patients with dislocation fractures of forearm bones to reach the earliest possible and complete restoration of functions of injured limbs. The research is of clinic- radiological character and is based on the investigation of treatment results of 74 patients with dislocation fractures of forearm bones who were treated with different methods during the years of 2001-2007. The algorithm of examination of that category of patients was developed taking into account the damage of the components of stability of the elbow. The indications for conservative and surgical methods of treatment of patients with dislocation fracture of forearm bones were defined depending on the severity and nature of the damage. Rehabilitation program for such patients was offered regarding the category of the injury. The method of integrated assessment of anatomical and functional results of treatment of dislocation fractures of forearm bones was worked out.

Received: 2013-06-17

Published online: 2017-01-05

DOI:

Comments 0

VIEWS 4338

Zhavoronkov EA, Skoroglyadov AV, Ratjev AP, Korobushkin GV

The aim of the investigation was to create an effective system of treating patients with isolated fractures of the radial head in order to achieve the most rapid and full recovery of the injured limb function. The work is based on the study of the results of treatment of 89 patients with isolated fractures of the radial head treated by various methods from 2005 to 2011. It was developed an algorithm for investigation of such patients providing a detailed analysis of the various options for fractures of the radial head. Applied in the work classification of Mason in Hotchkiss modification helps to determine the treatment strategy and predict functional outcome. The developed system of treating patients with fractures of the radial head takes into account the severity of damage and includes indications for conservative and operative treatment, makes it possible to obtain good functional results.

Received: 2013-06-17

Published online: 2017-01-05

DOI:

Comments 0

VIEWS 4588

Ivkov AV, Sirotin IV, Karapetyan KS, Skoroglyadov AV

A new guiding device for osteosynthesis of femoral neck fractures with three screws was worked out at the Department of Traumatology, Orthopedics and Battle-Field Surgery of Pirogov Russian National Research Medical University. The main distinctive feature of the guider is the opportunity of performing holes in a bone with the use of not only needles as it was presented in previous models but with the use of a drill, and the opportunity of inputting the screws. The results of osteosynthesis using new guide were regarded as good ones and wonderful.

Received: 2013-06-17

Published online: 2017-01-05

DOI:

Comments 0

VIEWS 4630