Miscellaneous To the problem of system forming factors of modern university education
Morgun AN
The aim of this research is the rationalization of the innovation system-factor of modern university education. The analysis of the present situation in university's education was conducted in terms of trends in the continuum of individualism-corporatism. A trend to the atomization of interests was shown as the main motivational factors of modern education, the entropic dynamic character of resource development was shown, the lack of their consolidating component. The characteristics of the necessary system-factor were given.
Received: 2011-12-19
Published online: 2017-01-05
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VIEWS 4153
Review Present capabilities of brain circulation evaluation and level of cerebral perfusion in patients with brachiocephalic arteries occlusive disease
Askanidi IP, Pyshkina LI, Serguladze TN
The article contains modern data review of a brain perfusion on extra- and intracranial levels during occlusion diseases of brachiocephalic arteries. In patients with brain ischemia there were described the possibilities of assessing the level of perfusion by noninvasive methods: single-proton emission computed tomography with <sup>99m</sup>Tc-HMPAO and ultrasound diagnostic methods with functional loading tests.
Received: 2012-04-18
Published online: 2017-01-05
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VIEWS 4182
Original research Clinical forms of tuberculosis in infants and preschool children with carriage of herpes viruses in the blood mononuclear cells
Panova OV, Stakhanov VA, Stenina MA, Voevodin DA, Krivov LI
The aim of the study was to evaluate the clinical features of the course of tuberculosis in infants and preschool children against herpes infection. The presence of viral infection was noted on detection of DNA viruses: the Epstein-Barr virus, herpes simplex virus type VI, cytomegalovirus in blood mononuclear cells of children. According to the results of PCR diagnosis, 28 (the 1st group) of the 61 children surveyed were infected with herpes viruses, 33 children (the 2nd group) — were not infected with those viruses. The frequency of comorbidity was higher in the 1st group. 12 of 14 children diagnosed with tuberculosis intoxication were infected with herpes viruses. Tuberculosis intoxication in the structure of the clinical forms of tuberculosis in the 1st group was 43 %, and in the 2nd group was only 6 %. The role of viral suppression of dendritic cells as a possible factor in the suppression of specific immune response to Mycobacterium tuberculosis in the mediastinal lymph nodes and the emergence of "minor" forms of tuberculosis in children was discussed.  
Received: 2012-04-18
Published online: 2017-01-05
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VIEWS 4210
Review Surgical treatment of Peyronie’s disease. Part 1. The possibilities of the human body
Nazarenko GI, Darenkov SP, Zyryanova ON, Sakrisyan AD
The article is devoted to modern techniques of surgical treatment of Peyronie's disease. To date, surgery is the main effective means of therapy of this symptomatic disease. There is proposed a set of techniques that can be divided into two groups of operations: shortening (Nesbit operation and its modifications, plication) and lengthening (patchwork) corporoplasty. Shortening techniques proved to be effective, and subjected to certain indications for their use, are considered satisfactory by professionals and patients. Among them the most preferred are modified Nesbit operations. When prolonging corporoplasty today probably there is no need for complete excision of the plaque, and the most contentious issue is the selection of optimal plastic automaterial. The author presented a case of his own experience of surgical treatment of Peyronie's disease symptom.
Received: 2012-04-04
Published online: 2017-01-05
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VIEWS 4319
Original research Personalized immunotherapy in the treatment of hypertrophy of adenoid vegetation
in children
Kovalchuk LV, Gankovskaya LV, Rakhmanova IV, Svitich OA, Zinker GM, Gankovskiy VA, Kartashov DD, Volkova YuV, Russanova KV
The results of the study of the effectiveness of personalized immunotherapy in children with hypertrophy of II–III degree adenoid vegetations are presented in the article. It was established, that application of autologous complex of immunopeptides including cytokines and antimicrobial peptides produced by white blood cells of the patients, led to the normalization of nasal breathing, a reduction in the frequency of otitis and of respiratory viral infections at 6 months observation after the treatment. There were identified individual differences in gene expression of molecules of the innate immunity in the mucosa of the nasal cavity, what provides the personalized approach to immunotherapy.
Received: 2012-04-17
Published online: 2017-01-05
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VIEWS 4452
Original research Impulse activity of medullar cardiovascular neurons during hypoxia and hypercapnia
Mikhaylova SD, Semushkina TM, Sokolov AV, Mikaelyan NP, Storozhakov GI
In the acute experiments on rabbits there was discovered an impulse activity of afferent and interneurons of the medullar cardiovascular center in the conditions of hypoxia and hypercapnia. Afferent neurons received information on myelinated fibers of vagus nerve and caused reaction on hypercapnia in one per three cases. Interneurons received information simultaneously on both myelinated and unmyelinated fibers of vagus nerves. They reacted both on hypoxia and hypercapnia.
Received: 2012-01-30
Published online: 2017-01-05
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VIEWS 4253
Original research Effect of cryoglobulins on electrophoretic mobility of erythrocytes in various diseases
Konstantinova NA, Kulikova IYu, Karandashov EN
The temperature dependence of the electrophoretic mobility of erythrocytes loaded with cryoglobulins, isolated from serum of patients with various diseases and different forms of a disease (systemic lupus erythematosus, chronic glomerulonephritis, atherothrombotic and cardioembolic ischemic stroke options) was investigated. Erythrocytes were obtained from healthy donors' blood. It was established that cryoglobulins significantly changed electrophoretic mobility of erythrocytes. This change may be in different directions: both upward and downward, depending on the nature of the disease and forms of its manifestation. It was shown that cryoglobulins complexes decompose at elevated temperatures. It was concluded that the electrophoretic method for estimating cryocomplexes is quite informative, in particular, to assess the extent of their heterogeneity.
Received: 2012-04-17
Published online: 2017-01-05
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VIEWS 4063
Editorial To the 80th anniversary of Yury Andreevich Vladimirov
Abstract has not been added yet...
Received: 2011-12-19
Published online: 2017-01-05
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VIEWS 2320