ORIGINAL RESEARCH

Significance of miR-146a quantification in human blood plasma for the diagnosis of colorectal cancer

Shirshova AN1, Shamovskaya DA1, Boyarskikh UA1, Apalko SV2, Leskov LS3, Sokolov AV, Kovalenko SA2, Scherbak SG2, Pikalov IV4, Kel AE1, Filipenko ML1,5
About authors

1 Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia

2 City Hospital No. 40, Saint Petersburg, Russia

3 City Clinical Hospital No. 1, Novosibirsk, Russia

4 Novosibirsk State Medical University, Novosibirsk, Russia

5 Novosibirsk State University, Novosibirsk, Russia

Correspondence should be addressed: Maxim L. Filipenko
Prospekt Ak. Lavrientieva, d. 8, Novosibirsk, Russia, 630090; ur.csn.hcobin@xam

About paper

Funding: this works was supported by the Federal Targeted Program for Research and Development in Priority Areas of Advancement of the Russian Scientific and Technological Complex for 2014–2020 (Grant No. 14.604.21.0101, ID RFMEFI60414X0101).

All authors' contribution to this work is equal: selection and analysis of literature, research planning, data collection, analysis, and interpretation, drafting of a manuscript, editing.

Received: 2017-08-25 Accepted: 2017-08-30 Published online: 2017-10-30
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  1. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A. 2008 Jul 29; 105 (30): 10513–8. DOI: 10.1073/pnas.0804549105.
  2. Olivieri F, Rippo MR, Monsurrò V, Salvioli S, Capri M, Procopio AD, Franceschi C. MicroRNAs linking inflamm-aging, cellular senescence and cancer. Ageing Res Rev. 2013 Sep; 12 (4): 1056–68. DOI: 10.1016/j.arr.2013.05.001.
  3. Dlouhá D, Hubáček JA. Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. Physiol Res. 2017 Apr 5; 66 (Supplementum 1): S21–S38.
  4. Giral H, Kratzer A, Landmesser U. MicroRNAs in lipid metabolism and atherosclerosis. Best Pract Res Clin Endocrinol Metab. 2016 Oct; 30 (5): 665–76. DOI: 10.1016/j.beem.2016.11.010.
  5. Victoria B, Nunez Lopez YO, Masternak MM. MicroRNAs and the metabolic hallmarks of aging. Mol Cell Endocrinol. 2017 Jan 5; 455: 131–47. DOI: 10.1016/j.mce.2016.12.021.
  6. Moridikia A, Mirzaei H, Sahebkar A, Salimian J. MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer. J Cell Physiol. 2017 Jan 16. DOI: 10.1002/jcp.25801.
  7. Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res. 2003 Oct; 1 (12): 882–91.
  8. Li HG, Zhao LH, Bao XB, Sun PC, Zhai BP. Meta-analysis of the differentially expressed colorectal cancer-related microRNA expression profiles. Eur Rev Med Pharmacol Sci. 2014; 18 (14): 2048–57.
  9. Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, Guo J et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008 Oct; 18 (10): 997–1006. DOI: 10.1038/cr.2008.282.
  10. Ng EK, Chong WW, Jin H, Lam EK, Shin VY, Yu J et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut. 2009 Oct; 58 (10): 1375–81. DOI: 10.1136/gut.2008.167817.
  11. Clancy C, Joyce MR, Kerin MJ. The use of circulating microRNAs as diagnostic biomarkers in colorectal cancer. Cancer Biomark. 2015; 15 (2): 103–13. DOI: 10.3233/CBM-140456.
  12. Yuan Z, Baker K, Redman MW, Wang L, Adams SV, Yu M et al. Dynamic plasma microRNAs are biomarkers for prognosis and early detection of recurrence in colorectal cancer. Br J Cancer. Epub 2017 Aug 15. DOI: 10.1038/bjc.2017.266.
  13. SysCol [Internet]. Huddinge, Sweden: Karolinska Institutet [cited 2017 Aug]. Available from: http://syscol-project.eu.
  14. Eng J. ROC analysis: web-based calculator for ROC curves. Baltimore: Johns Hopkins University [updated 2014 Mar 19; cited 2017 Aug]. Available from: http://www.jrocfit.org.
  15. Yang Y, Gu X, Zhou M, Xiang J, Chen Z. Serum microRNAs: A new diagnostic method for colorectal cancer. Biomed Rep. 2013 Jul; 1 (4): 495–8. DOI: 10.3892/br.2013.109.
  16. Zekri AR, Youssef AS1, Lotfy MM, Gabr R, Ahmed OS, Nassar A et al. Circulating Serum miRNAs as Diagnostic Markers for Colorectal Cancer. PLoS One. 2016 May 2; 11 (5): e0154130. DOI: 10.1371/journal.pone.0154130.
  17. Rusca N, Monticelli S. MiR-146a in immunity and disease. Mol Biol Int. 2011; 2011: 437301. DOI: 10.4061/2011/437301.
  18. Magilnick N, Reyes EY, Wang WL, Vonderfecht SL, Gohda J, Inoue JI et al. miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression. Proc Natl Acad Sci U S A. 2017 Aug 22; 114 (34): E7140–9. DOI: 10.1073/pnas.1706833114.
  19. Han Y, Li Y, Jiang Y. The Prognostic Value of Plasma MicroRNA-155 and MicroRNA-146a Level in Severe Sepsis and Sepsis-Induced Acute Lung Injury Patients. Clin Lab. 2016 Dec 1; 62 (12): 2355–60. DOI: 10.7754/Clin.Lab.2016.160511.
  20. Xie M, Li Y, Wu J, Wu J. A risk of digestive tract neoplasms susceptibility in miR-146a and miR-196a2. Fam Cancer. 2015 Jun; 14 (2): 229–39. DOI: 10.1007/s10689-014-9776-6.
  21. Sun Y, Li M. Genetic polymorphism of miR-146a is associated with gastric cancer risk: a meta-analysis. Eur J Cancer Care (Engl). 2017 Mar; 26 (2). DOI: 10.1111/ecc.12355.
  22. Zhou X, Zhu W, Li H, Wen W, Cheng W, Wang F et al. Diagnostic value of a plasma microRNA signature in gastric cancer: a microRNA expression analysis. Sci Rep. 2015 Jun 10; 5: 11251.
  23. Pihlstrøm L, Rengmark A, Bjørnarå KA, Toft M. Effective variant detection by targeted deep sequencing of DNA pools: an example from Parkinson's disease. Ann Hum Genet. 2014 May; 78 (3): 243–52. DOI: 10.1111/ahg.12060.
  24. Otsu H, Watanabe M, Inoue N, Masutani R, Iwatani Y. Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases. Clin Chem Lab Med. 2017 May 1; 55 (5): 626–35. DOI: 10.1515/cclm-2016-0449.