2019 / 02

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DOI: 10.24075/brsmu.2019.021
Copyright: © 2019 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Dynamics of hemostasis parameters and endothelial dysfunction markers in patients with thermal injury

Morrison VV1, Bozhedomov AYu2
About authors

1 Saratov State Medical University, Saratov, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Alexey Yu. Bozhedomov
Ostrovityanova 1, Moscow, 117997; ur.liam@48_oscela

About paper

Author contribution: Morrison VV — design of the experiment, data analysis, manuscript revision; Bozhedomov AYu — data collection and statistical analysis, manuscript draft.

Received: 2018-12-28 Accepted: 2019-03-26 Published online: 2019-04-08
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Table 1. Markers of endothelial dysfunction
Table 2. Hemostasis dynamics in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 3. Cytokine dynamics in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 4. Dynamics of endothelial dysfunction markers in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 5. Differences in the values of blood coagulation parameters in burn patients with normal coagulation and coagulopathy, M ± σ
Note: * — the difference between the two groups is significant (p < 0.05).
Table 6. Differences in the levels of cytokines and endothelial dysfunction markers in burn patients with normal coagulation and coagulopathy, M ± σ
Note: * — the difference between the two groups is significant (p < 0.05).