ORIGINAL RESEARCH

Dynamics of hemostasis parameters and endothelial dysfunction markers in patients with thermal injury

Morrison VV1, Bozhedomov AYu2
About authors

1 Saratov State Medical University, Saratov, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Alexey Yu. Bozhedomov
Ostrovityanova 1, Moscow, 117997; ur.liam@48_oscela

About paper

Author contribution: Morrison VV — design of the experiment, data analysis, manuscript revision; Bozhedomov AYu — data collection and statistical analysis, manuscript draft.

Received: 2018-12-28 Accepted: 2019-03-26 Published online: 2019-04-08
|
  1. Dumnicka P, Maduzia D, Ceranowicz P, et al. The Interplay between Inflammation, Coagulation and Endothelial Injury in the Early Phase of Acute Pancreatitis: Clinical Implications. Int J Mol Sci. 2017; 18 (2): E354. DOI: 10.3390/ijms18020354. PubMed PMID: 28208708.
  2. Alekseev AA, Ushakova TA, Krutikov MG, Bobrovnikov AYe. Markery sepsisa v diagnostike adaptivnogo vospalenija pri ozhogovoj travme. Lechenie i profilaktika. 2015; 2 (14): 84–91. Russian.
  3. Ushakova TA. Adaptacija k ozhogovoj travme: problemy i perspektivy. Kombustiologija. 2009; 39. Dostupno po ssylke: www.combustiolog.ru (data obrashhenija 23.06.2018). Russian.
  4. Chousterman BG, Swirski FK, Weber GF. Cytokine storm and sepsis disease pathogenesis. Semin Immunopathol. 2017; 39 (5): 517–28.
  5. Ince C, Mayeux PR, Nguyen T, et al. The endothelium in sepsis. Shock. 2016; 45 (3): 259–70.
  6. Abdel-Hafez NM, Saleh Hassan Y, El-Metwally TH. A study on biomarkers, cytokines, and growth factors in children with burn injuries. Ann Burns Fire Disasters. 2007; 20 (2): 89–100.
  7. Petrishhev NN, Berkovich OA, Vlasov TD i dr. Diagnosticheskaja cennost' opredelenija deskvamirovannyh jendotelial'nyh kletok v krovi. Klinicheskaja laboratornaja diagnostika. 2001; (1): 50–2. Russian.
  8. Gavrilenko TI, Ryzhkova NA, Parhomenko AN. Sosudistyj jendotelial'nyj faktor rosta v klinike vnutrennih zabolevanij i ego patogeneticheskoe znachenie. Ukraїns'kij kardіologіchnij zhurnal. 2011; (4): 87–95. Russian.
  9. Erdbruegger U, Haubitez M, Woywodt A. Circulating endothelial cells: a novel marker of endothelial damage. Clinica Chimica Acta. 2006; (373): 17–26.
  10. Dremina NN, Shurygin MG, Shurygina IA. Jendoteliny v norme i patologii. Mezhdunarodnyj zhurnal prikladnyh i fundamental'nyh issledovanij. 2016; (10): 210–14. Russian.
  11. Yanagisawa M, Masaki T. Molecular biology and biochemistry of the endothelins. Trends Pharmacol Sci. 1989; 10 (9): 374–8.
  12. Morrison VV, Bozhedomov AYu. Disfunkcija jendotelija pri sindrome poliorgannoj nedostatochnosti u bol'nyh s termicheskoj travmoj. Regionarnoe krovoobrashhenie i mikrocirkuljacija. 2013; 2 (46): 43–8. Russian.
  13. Iba T, Kidokoro A, Fukunaga M, et al. Association between the severity of sepsis and the changes in hemostatic molecular markers and vascular endothelial damage markers. Shock. 2005; 23 (1): 25–9.
  14. Firsov SA, Matveev RP. Jendotelial'naja disfunkcija i ee prognosticheskoe znachenie pri kriticheskih sostojanijah v rezul'tate dorozhno-transportnogo travmatizma. Sovremennye problemy nauki i obrazovanija. 2014; 6. Dostupno po ssylke: http://science-education.ru/ru/article/view?id=16629 (data obrashhenija: 24.03.2019). Russian.
  15. Scharpfenecker M, Fiedler U, Reiss Y, Augustin HG. The Tie-2 ligandangiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism. J Cell Sci. 2005; 118 (4): 771–80.
  16. Abo El-Noor MM, Elgazzar FM, Alshenawy HA. Role of inducible nitric oxide synthase and interleukin-6 expression in estimation of skin burn age and vitality. J Forensic Leg Med. 2017; (52): 148–53.