ORIGINAL RESEARCH

Analysis of associations of polymorphisms in the genes coding for L4, IL10, IL13 with the development of atopic bronchial asthma and its remission

Zhorina YuV1, Abramovskikh OS1, Ignatova GL1, Ploshchanskay OG2
About authors

1 South Ural State Medical University, Chelyabinsk, Russia

2 DNA Clinic LLC, Chelyabinsk, Russia

Correspondence should be addressed: Yulia Yu. Zhorina
Vorovskogo, 64, Chelyabinsk, 454092; ur.liam@42tramailuj

About paper

Author contribution: Zhorina YuV — conceived and planned the study, collected, processed and interpreted the data, performed statistical analysis, participated in writing the manuscript; Abramovskikh OS — proposed the method and supervised the study, analyzed and interpreted the data, participated in writing the manuscript; Ignatova GL — analyzed the clinical data, supervised the study, interpreted the data, participated in writing the manuscript; Ploshchanskay OG — collected the data, conducted laboratory tests, interpreted the data and participated in writing the manuscript.

Received: 2019-09-25 Accepted: 2019-10-11 Published online: 2019-10-22
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Table 1. Spirometry test results in patients with atopic BA remission, without remission and in the controls
Table 2. Genotype frequency distribution for SNPs in the interleukin genes in patients with atopic BA and the controls
Table 3. Frequency of SNP genotypes of interleukin genes in patients with atopic BA remission and without it