2020 / 01

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DOI: 10.24075/brsmu.2020.002

ORIGINAL RESEARCH

The effect of acute somatic pain on the killing activity of neutrophils in newborn rats

Alekseev VV1, Kade AKh2
About authors

1 Rostov State Medical University, Rostov-on-Don, Russia

2 Kuban State Medical University, Krasnodar, Russia

Correspondence should be addressed: Vladimir V. Alexeev
Per. Nakhichevansky, 29, Rostov-on-Don, 344022; moc.liamg@119veexela

About paper

Acknowledgements: the authors thank Ovsyannikov VG, Head of the Department of Pathologic Physiology (Rostov State Medical University) and Boychenko AE, Professor at the Department of Pathologic Physiology, for their valuable advice and feedback; Aboyan IA, Chief Physician of the Clinical Diagnostic Center Health, for granting access to the laboratory equipment of the Center.

Author contribution: Alexeev VV conducted the experiment, analyzed and interpreted the obtained results, wrote the manuscript; Kade AKh conceived and designed the study, revised the manuscript for intellectual content and made final corrections.

Received: 2019-12-17 Accepted: 2020-01-07 Published online: 2020-01-20
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Fig. 1. Dynamics of the spontaneous NBT reduction test in newborn rats before and after exposure to the algogenic stimulus. * * — differences are significant between the main group and the control animals (p ≤ 0.05)
Fig. 2. Dynamics of the stimulated NBT reduction test in newborn rats before and after exposure to the algogenic stimulus. * * — differences are significant between the main group and the control animals (p ≤ 0.05)
Fig. 3. Dynamics of the microbicidal activity coefficient in newborn rats before and after exposure to the algogenic stimulus.* * — differences are significant between the main group and the control animals (p ≤ 0.05)