ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Immunohistochemical expression of Nanog protein in prostate cancer cells of distinct grade groups
About authors
1 Peoples’ Friendship University of Russia, Moscow, Russia
2 Research Institute of Human Morphology, Moscow, Russia
3 Hospital for War Veterans № 2, Moscow, Russia
Correspondence should be addressed: Georgy Yu. Kudryavtsev
Baikalskaya, 35, apt. 216, Moscow, 107207; ur.liam@ahsogk
About paper
Compliance with ethical standards: the study was approved by the Ethics Committee of Medical Institute of the Peoples' Friendship University of Russia (protocol № 13 dated December 19, 2019); the study design was consistent with the Declaration of Helsinki guidelines regarding the research involving identifiable human tissue samples. The informed consent was submitted by all patients.
Author contribution: Kudryavtsev GYu, Kudryavtsevа YaYu, Solovyeva NA — literature survey, manuscript writing; Kudryavtseva LV, Osipov VA — statistical data processing; Mikhaleva LM — sample collection and processing; Babichenko II — study concept and design.
Received: 2020-10-06
Accepted: 2020-10-20
Published online: 2020-10-31
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Fig. 1. Expression of Ki-67 in patients with benign prostatic hyperplasia and prostate adenocarcinoma
Fig. 2. Comparison of Ki-67 expression between different prostate cancer Grade Groups
Fig. 3. Comparison of Nanog expression between different prostate cancer Grade Groups
Fig. 4. Expression of Ki-67 and Nanog in the prostate cancer cells for the most common Gleason patterns (magnification х400)
Table. Relationship between the expression of Ki-67 and Nanog and the major clinical and morphological characteristics
