ORIGINAL RESEARCH

Local antioxidant effect of original dermal film with melatonin in thermal injury

Osikov MV1, Simonyan EV1, Ageeva AA1, Ageev YuI1, Fedosov AA2, Sinitsky AI1
About authors

1 South-Ural State Medical University, Chelyabinsk, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Anna A. Ageeva
Vorovskogo, 64, Chelyabinsk, 454092; ur.xednay@r.aveega.enna

About paper

Compliance with ethical standards: the study was approved by the Ethics Committee of the South Ural State Medical University, Chelyabinsk (Minutes #10 of November 15, 2019), carried out in standard vivarium conditions with strict adherence to the requirements for animal keeping and care, as well as withdrawal of animals from the experiment and subsequent disposal in accordance with the European Convention for the Protection of Vertebrate Animals used for Experimental or Other Scientific Purposes (ETS № 123 of March 18, 1986, Strasbourg), EC Recommendations 2007/52/EC of June 18, 2007 outlining procedures of keeping and care for animals used for experimental and other scientific purposes, as well as the European Parliament and EU Council Directive 2010/63/EU of September 22, 2010 on protection of animals used for scientific purposes as governed by the rules of humane treatment of animals, guidelines for their withdrawal from experiments and euthanasia.

Author contribution: MV Osikov — study concept and design, integrated analysis of the data obtained, authoring, manuscript editing; EV Simonyan — experimental material collection, analysis of the data obtained; AA Ageeva — experimental material collection, statistical processing and analysis of the data obtained, authoring; YuI Ageev — experimental material collection, statistical processing and analysis of the data obtained; AA Fedosov — analysis of the results, manuscript editing; AI Sinitsky — experimental material collection, manuscript editing.

Received: 2020-10-03 Accepted: 2020-10-23 Published online: 2020-11-11
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