2021 / 04

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DOI: 10.24075/brsmu.2021.038

ORIGINAL RESEARCH

Experimental assessment of biological potential of collagen membranes in reconstruction of full-thickness hyaline cartilage defects

Lazishvili GD1, Egiazaryan KA1, Nikishin DV2, Voroncov AA3, Klinov DV4
About authors

1 Pirogov Russian National Research Medical University, Moscow, Russia

2 OOO Aptos Group, Moscow, Russia

3 Doctor Vorontsov's Veterinary Center for Surgery and Oncology, Moscow, Russia

4 Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia

Correspondence should be addressed: Guram D. Lazishvili
Ostrovityanova, 1, 117997, Moscow; moc.liamg@zalmarug

About paper

Author contribution: Lazishvili GD — design of the experiment, participation in the experimental surgery, analysis of literature and experimental materials, article authoring; Yeghiazaryan KA — analysis of literature, experimental results; Nikishin DV — processing and analysis of the experimental data, article authoring; Vorontsov AA — execution of the experimental surgery; Klinov DV — Ortokeep collagen membrane design and development.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Center for Preclinical Research of Penza (Minutes № 1–19 of March 11, 2019). The animals were kept and used in compliance with the ethical standards and International requirements for humane treatment of laboratory (experimental) animals, as well as GOST R ISO 10993-1-2009 Medical Devices.

Received: 2021-07-19 Accepted: 2021-08-05 Published online: 2021-08-20
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