OPINION

Metabolic engineering is a promising way to generate highly effective producers of bioactive substances

Blokhina AE1,2, Palkina KA1, Shakhova ES1, Malyshevskaia AK1,2, Osipova ZM1,3, Myshkina NM1
About authors

1 Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

2 Lomonosov Moscow State University, Moscow, Russia

3 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Nadezhda M. Myshkina
Miklukho-Maklaya, 16/10, Moscow, 117997, Russia; moc.liamg@aydan.anikram

About paper

Funding: the study was supported by the Russian Science Foundation Grant № 21-74-00075, https://rscf.ru/project/21-74-00075/

Acknowledgements: the authors would like to thank A.S. Sheglov, research fellow at the Laboratory of Chemistry of Metabolic Pathways, for valuable criticisms.

Author contribution: Blokhina AE, Palkina KA, Shakhova ES, Malyshevskaia AK, Osipova ZM — literature review, data processing; Myshkina NM — literature review, data processing, project management, manuscript writing.

Received: 2023-04-05 Accepted: 2023-04-19 Published online: 2023-04-26
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Fig. Scheme of contemporary approach of generating bioactive compounds in heterologous hosts