ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Gut microbiota alterations and their association with IL6, IL8 and TNFα levels in patients with external genital endometriosis
About authors
SI Georgievsky Medical Academy, VI Vernadsky Crimean Federal University, Simferopol, Russia
Correspondence should be addressed: Lesya Nikolaevna Gumenyuk
Bulvar Lenina, 5/7295006, Simferopol, Republic of Crimea, Russia; ur.liam@anikoros.ayel
About paper
Author contribution: Gumenyuk LN — study concept and design; Zemlyanaya IA, Rami A, Seroshtanov NA — data acquisition, analysis, and interpretation; Badula ES, Ismailov AR — statistical data processing; Kokareva SS, Cheremisova AA, Kupreichyuk YuR — manuscript writing.
Compliance with ethical standards: the study was approved by the Ethics Committee of the SI Georgievsky Medical Academy, VI Vernadsky Crimean Federal University (protocol № 10 of 14 November 2021), planned and conducted in accordance with the Declaration of Helsinki. The informed consent was obtained from all study participants.
Received: 2023-01-13
Accepted: 2023-05-15
Published online: 2023-06-15
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Fig. 1. Phylogenetic composition of gut microbiota in patients with external genital endometriosis (EGE) and healthy women. CG — control group
Fig. 2. Species composition of gut microbiota in patients with external genital endometriosis (EGE) and healthy women. CG — control group
Table 1. Characteristics of patients with external genital endometriosis and healthy women
Table 2. Comparative analysis of plasma IL6, IL8 and TNFα levels in patients with external genital endometriosis (EGE) and healthy women. CG — control group; р — significance of differences between the values of patients with EGE and the CG
