ORIGINAL RESEARCH
Apoptosis of granulosa cells in women with impaired reproductive function and extragenital pathology
1 Volgograd State Medical University of the Ministry of Health of the Russian Federation, Volgograd, Russia
2 Innovative Medicines R&D and Piloting Center, Volgograd, Russia
3 Department of Assisted Reproductive Technologies. Multidisciplinary Clinic No. 1, Volgograd, Russia
Correspondence should be addressed: Danil S. Lipov
Vysokaya, 18a, Volgograd, 400127, Russia; ur.xednay@vopillinad
Author contribution: LN Rogova — study planning, data analysis and interpretation; DS Lipov — manuscript authoring, analysis of the study data; VN Perfilova, MV Kustova — determination of the level of apoptosis in granulosa cells by flow cytometry; AV Mukhina — collection of the granulosa cell samples from patients; DA Churzin — analysis of the published papers, statistical processing of the obtained data.
Compliance with ethical standards: the study was approved by the Ethics Committee of the Volgograd State Medical University (Minutes № 2021/053 of May 27, 2021) and conducted in compliance with the ethics principles of the WMA Declaration of Helsinki (2000). All donors have voluntarily signed the participant consent forms.