Funding: the study was supported by the RSF (research project No. 23-25-00346).

Author contribution: Marzol EA, Dvornichenko MV — developing concept and design; Marzol EA, Aparshev NA, Mitryaikin NS — data analysis and interpretation; Marzol EA, Mitryaikin NS, Dvornichenko MV — substantiation of manuscript or verification of critical intellectual content; Dvornichenko MV — final approval of manuscript before publishing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Siberian State Medical University (protocol No. CDI-005 dated 5 February 2022). Animals were handled in accordance with the Directive 2010/63/EU of the European Parliament and the Council on the protection of animals used for scientific purposes dated 22 September 2010, rules and regulations of the European Community (86/609EEC), Declaration of Helsinki, and orders of the Ministry of Health of the USSR (No. 742 dated 13 November 1984 and No. 48 dated 23 January 1985).