2025 / 01

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DOI: 10.24075/brsmu.2025.009
Copyright: © 2025 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

The effect of sterilization methods on the cytotoxicity of ceramic medical implants

Bilyalov AR, Piatnitskaia SV, Rafikova GA, Akbashev VN, Bikmeyev AT, Akhatov ISh, Shangina OR, Chugunov SS, Tikhonov AA
About authors

Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa, Russia

Correspondence should be addressed: Azat R. Bilyalov
Lenina, 3, ap. 119, 450008, Ufa, Republic of Bashkortostan, Russia; moc.liamg@volaylib.taza

About paper

Funding: the work was supported by the Russian Science Foundation under grant No. 23-15-20042.

Author contribution: Bilyalov AR — stuidy conceptualization, data analysis, article editing; Piatnitskaia SV — cytotoxicity evaluation (MTT test), analysis of the results; Rafikova GA — preparation of digital models and sample production, analysis of mechanical and biological properties of materials; Akbashev VN — sterilization experiments, analysis of the effect of sterilization methods on materials; Bikmeyev AT — mathematical modeling of material parameters, interpretation of the data obtained; Akhatov IS — coordination of work, general guidance, article editing; Shangina OR — analysis of the samples' porosity and density, statistical data processing; Chugunov SS — samples heat treatment and sintering, description of materials and methods; Tikhonov AA — assessment of microstructural changes using SEM, writing the section "Electron microscopy."

Received: 2024-12-14 Accepted: 2025-02-18 Published online: 2025-02-27
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