Funding: the study was conducted within the framework of the basic budgetary funding source for project of the State Assignment of the Ministry of Health of the Russian Federation (agreement No. 056-03-2023-050 dated 17.01.2023).

Author contribution: Meyer AV, Lavryashina MB — developing the study concept and design, manuscript writing and final approval; Thorenko BA — genotyping, statistical analysis, working with the database; Imekina DO — genotyping, statistical analysis, technical editing; Dutchenko AP — search for literature, manuscript writing; Pyanzova TV — research management, clinical and biological material collection, final approval of the manuscript; Karabchukov KB — clinical history taking.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Kemerovo State Medical University (protocol No. 301 dated 08 February 2023) and conducted in accordance with the ethical principles stated in the WMA Declaraction of Helsinki; the written informed consent to participation in the study was obtained from all patients.