2026 / 02

DOI: 10.24075/brsmu.2026.009
Copyright: © 2026 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Early administration of xenon-oxygen mixture in neonatal hypoxic-ischemic encephalopathy

Dementev IM1,2 , Gabitov MV1 , Timoshin SS2 , Kuzovlev AN1 , Grebenchikov OA1
About authors

1 Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia

2 Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia

Correspondence should be addressed: Mikhail V. Gabitov
Petrovka 25, str. 2, Moscow, 107031, ur.rrcknf@votibagm

About paper

Funding: the work was carried out under the research project "Cytoprotective Effects of Inert Gases for the Prevention and Treatment of Organ Dysfunction in Critical Conditions" (No. FGWS-2025-0015).

Author contribution: Dementev IM — conducting the model experiment, analysis and discussion of results, manuscript writing; Gabitov MV — analysis of results, statistical analysis, manuscript writing and editing; Timoshin SS — discussion of results and manuscript editing; Kuzovlev AN — study planning, discussion of results, manuscript editing; Grebenchikov OA — approval of the study design, discussion of results, manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology (Protocol No. 2/25/5 dated March 26, 2025). All animal procedures were performed in accordance with the principles of the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes (Strasbourg, 1986). The report of the study was prepared in accordance with the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines.

Received: 2026-02-25 Accepted: 2026-03-10 Published online: 2026-03-17
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