Bulletin of RSMU

ISSN Print 2500–1094 ISSN Online 2542–1204

BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Filatova LA, Saprykina LV, Kheydar LA, Dobrokhotova YuE

The purpose of the investigation is to study the role of combined oral contraceptives (COCs) in the rehabilitation of patients after surgery for an ectopic pregnancy. 27 patients after surgery for the ectopic pregnancy were examined. The patients were divided into 2 groups. For the purpose of contraception and rehabilitation the patients of the 1st group received COC (30 meg ethinylestradiol and 150 meg desogestrel); the 2nd group did not receive it. There was observed a good control of the menstrual cycle, lack of intermenstrual bleeding in the patients of the 1st group. The indicated COC may be recommended after surgery for ectopic pregnancy.

Received: 2014-10-07

Published online: 2017-01-05

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Ozolinya LA, Lapina IA, Nesterova AO

Hemostatic balance is provided by complex interactions of the coagulation, fibrinolytic systems, platelets and vascular wall. R.Virhov's work, published in 1856, laid the foundation for the study of the problems of thrombosis and first substantiated its etiopathogenesis: slowing the rate of blood flow, changes in blood, vascular wall damage. Further development of the doctrine of thrombosis significantly changed the idea of the significance of each of these factors. The review describes the recent literature data on this issue.

Received: 2014-10-07

Published online: 2017-01-05

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Kruglikov GG, Suslov VB, Likhacheva LM, Stranzha NB, Oettinger AP

The use of preparations-prints of the organs, blood smears and films of connective tissue revealed exaggerated forms of ciliated and goblet cells in patients with allergies, phagocytic activity of macrophages in experimental pneumoconiosis, increase in the number of atypical red blood cells in patients with toxic anemia and hypoxia (experimental pneumoconiosis), the features of morphology of mast cells in the embryons of experimental animals.

Received: 2014-08-25

Published online: 2017-01-05

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Anurov MA, Titkova SM, Oettinger AP

During the past 10 years, almost all researchers when systematizing of prostheses used for abdominal hernia repair indicated that the complex of properties, which affects a biological response and the nature of interaction with the surrounding tissue, depend on manufacturing techniques and structure of the prosthetic device. If summarize the literature data, five classes of prostheses can be distinguished now in accordance with the principle of construction, in which the type of the integration determines the application area and optimal methods of implantation. This approach enables to associate many modifications in each class and requires internal division of prostheses by groups using specially assigned criteria.

Received: 2014-10-15

Published online: 2017-01-05

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Bondarenko KR, Ozolinya LA, Bondarenko VM, Shpirko VO

The analysis of recent data on the study of the vaginal microbiota with normal microbiocenosis in pregnant and nonpregnant women is presented. Attention is drawn to particular relationships within the microbial community inhabiting the vaginal microecosystem of clinically healthy women during gestation. Some controversial issues concerning mechanisms for maintaining of vaginal microbiocenosis with Lactobacillus spp. are discussed.

Received: 2014-10-07

Published online: 2017-01-05

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Bakhareva IV, Gankovskaya LV, Magomedova AM, Kuznetsov PA, Romanovskaya VV, Mezentseva MV, Malushenko SV

The purpose of the study was the determination of diagnostic and prognostic value of a comprehensive research of interferon status in pregnant women with high infectious risk. 100 patients were investigated: 65 pregnant women with urogenital infections (UGI), 20 patients without UGI, who had labour in time and 15 non-pregnant women. The determining of interferon status and cellular sensitivity to interferon preparations was conducted by a biological method. It was found that in pregnant women with preterm birth (PB) in the context of high levels of IFN-γ gene its production in the culture of leukocytes was reduced, which indicates a violation of the production of IFN-γ at the posttranscriptional level. The ratio of induced production by peripheral blood leukocytes IFN-α and IFN-γ as 5 and more allows predicting the preterm birth with high accuracy (positive predictive value — 69 %, negative predictive value — 85.7 %, sensitivity — 90 %, specificity — 60 %).

Received: 2014-10-07

Published online: 2017-01-05

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Savchenko TN, Agaeva MI, Dergacheva IA

The presented review of literature is devoted to the actual problem of the influence of herpes infection on pregnancy. The spread of herpesvirus infection is global in nature. Over 90 % of people are infected with the herpes virus. Herpes infection is characterized by a variety of clinical forms with a predominance of atypical variants of the infectious process. The greatest risk of being infected with herpes viruses is during pregnancy because it can be a cause of miscarriage, intrauterine fetal infection, congenital malformations, as well as various pathologies of pregnancy.

Received: 2014-10-07

Published online: 2017-01-05

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Markova EA, Khashukoeva AZ, Svitich OA, Netudykhatko TV

The history of the photodynamic therapy (PDT) research, together with a virus infection as well, modern understanding of PDT-mechanisms and immunological aspects are reflected in the present literature review. There are outlined the latest scientific data on pre-clinical studies in the PDT and its use as an antitumor, antibacterial and antiviral therapy. The purpose of the review was to expand notions of antiviral PDT as a promising method for the treatment of viral infections, which are one of the proved causes of the recurrent pregnancy loss.

Received: 2014-10-07

Published online: 2017-01-05

DOI:

Comments 0