Bulletin of RSMU

ISSN Print 2500–1094 ISSN Online 2542–1204

BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Ishanova YuS, Dyakonova IN, Rakhmanova IV, Tikhomirov AM

The aim of the research was the comparative analysis of ototoxicity of amikacin and netromycin after their introduction to immature animals in therapeutic doses. As a result according to the registration of distortion-product otoacoustic emission and the record of short-latency auditory brainstem response more expressed toxic action of amikacin was revealed which was reflected in more substantial increase of thresholds of the 1st peak and greater decrease of its amplitude in comparison with the group of the animals receiving netromycin. Introduction of amikacin and netromycin took the same damaging effect on the area of outer hair cells responsible for the perception of frequencies 2 and 4 kHz.

Received: 2014-11-24

Published online: 2017-01-05

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Malygina LV, Denisova OA, Radtsig EYu

The definition of ENT-pathology infectious agent is a principal question. Urgent data on this problem are necessary for the choice of the right starting drug for empirical etiotropic therapy. The article describes methods being used for these purposes in patients with different forms of sinusitis, there is made a comparison of its practical significance.

Received: 2014-11-21

Published online: 2017-01-05

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Tyurkina SI, Minasyan VS, Savenkova MS

The peculiarities of chronic adenoiditis in 143 recurrently respiratory infected children with herpes viruses and intracellular pathogens were studied. A predisposing factor was the presence of an acute infection in the mother (13.3 %), or in family members (71.3 %) later. The prevalence of recurrent exudative otitis (52.4 %), confirmed by tympanometry, lymphadenitis of cervical group (58 %); hypertrophy of the pharyngeal tonsil III degree (57.3 %) with a predominance of purulent forms of acute exacerbation of chronic adenoiditis (73.4 %), caused by a mixed flora, was identified.

Received: 2014-11-21

Published online: 2017-01-05

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Bugaychuk OV, Radtsig EYu

In this article the results of the investigation of 391 patients (519 ears) aged 1 month to 15 years with an acute purulent otitis media (APOM) being under treatment in the ENT-department of the Morozov Children's Municipal Clinical Hospital are given. The etiological spectrum of pathogens of acute otitis media was defined. The sample for microbiological investigation was middle ear discharge taken by paracentesis (myringotomy) or fresh spontaneous perforation of the eardrum. Among etiologically decoded APOM 23.6 % were caused by Streptococcus pneumoniae. Repeated and/or recurrent APOM was identified in 52 % of investigated patients. It was concluded that a large number of APOM (46 %) with non-confirmed bacterial etiology require further study and the search for the causative agent of the disease.

Received: 2014-11-21

Published online: 2017-01-05

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Svistushkin VM, Egorov VI, Mustafaev DM, Volkova KB

Laryngeal papillomatosis is one of the important and unresolved problems of modern medicine. Tumor affects both children and adults, which is often fraught with serious life-threatening complications to the patient. The aim of the study was to evaluate the effectiveness of treatment of patients with laryngeal papillomatosis by using the combined method — cold plasma endolaryngeal microsurgery papillomas and inducers of an endogenous interferon therapy and activator of NK-killers (trade name Allokin-alpha) compared with the surgery without preventive treatment. The study included 50 patients, divided into two equal groups. In the study group, which consisted of 25 patients who received the combination treatment there increased an interrecurrent period and reduced the frequency of recuring. Thus, this method of treatment is recommended for the laryngeal papillomatosis.

Received: 2014-11-21

Published online: 2017-01-05

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Vasina AA, Radtsig EYu

Diseases of the vocal apparatus and state structures of the larynx are the least studied fields of pediatric otorhinolaryngology. Currently, the frequency of congenital abnormalities increases. This is due to the increase in the volume and improvement of the quality of diagnosis in childhood. This article describes the main methods of diagnosis of the larynx pathology, as well as data obtained by the authors in the study of its structure. There is described in details the structure of larynx pathology, which is characteristic for each age group, and there is traced its variation with age.

Received: 2014-11-21

Published online: 2017-01-05

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Kirichenko IM, Popadyuk VI

The article provides a brief review of the literature on the etiology and pathogenesis, clinic and methods of treatment of keloids. The clinical case of a large keloid of an auricle is considered. There was conducted a combined treatment of a patient with a positive clinical effect.

Received: 2014-11-21

Published online: 2017-01-05

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Svistushkin VM, Egorov VI, Zolotova AV, Shevchik EA

The aim of the work was to estimate the regeneration of the ear drum after the radiofrequency and laser myringotomy. 37 patients with otitis media with effusion were observed. In the 1st group (19 patients) perforation was performed using a radiofrequency device, in the 2nd group (18 patients) — with a laser. The evaluation of inflammatory changes of the tympanic membrane in the early postoperative period and the time of the perforation closure were estimated.

Received: 2014-11-21

Published online: 2017-01-05

DOI:

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