Copyright: © 2017 by the authors. Licensee: Pirogov University.
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ORIGINAL RESEARCH

Preliminary results of a controlled study of BCI-exoskeleton technology efficacy in patients with poststroke arm paresis

Frolov AA1,2 , Mokienko OA1,3 , Lyukmanov RKh1,3 , Chernikova LA3 , Kotov SV4 , Turbina LG4 , Bobrov PD1,2 , Biryukova EV1,2 , Kondur AA4 , Ivanova GE1 , Staritsyn AN1 , Bushkova YuV1 , Dzhalagoniya IZ2 , Kurganskaya ME2,3 , Pavlova OG2 , Budilin SYu2 , Aziatskaya GA3 , Khizhnikova AE3 , Chervyakov AV3 , Lukyanov AL5 , Nadareyshvily GG1
About authors

1 Institute of Higher Nervous Activity and Neurophysiology, RAS, Moscow, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

3 Research Center of Neurology, Moscow, Russia

4 Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

5 Municipal Clinical Hospital no. 31, Moscow, Russia

Correspondence should be addressed: Olesya A. Mokienko
Volokolamskoye shosse, d. 80, kab. 133, Moscow, Russia, 125367; ur.xednay@dm.aysel

About paper

Funding: the study was supported by the Ministry of Education and Science of the Russian Federation (Grant Agreement no. 14.607.21.0128 dated October 27, 2015), Russian Foundation Basic Research grants no. 16-04-01506а and 16-04-00962а.

Received: 2016-03-30 Accepted: 2016-04-07 Published online: 2017-01-05
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The article presents preliminary results of iMove research study. By the time of this publication, the data of 47 patients have been processed. The patients in the experimental group (n = 36) were trained in kinesthetic motor imagery using brain-computer interface (BCI) and a controllable exoskeleton. In the control group, BCI imitation procedures were carried out. In average, the patients had 9 training sessions with a duration of up to 40 minutes. On completing the training, only the experimental group showed improvement in scores (results are presented as median and quartiles (25 %; 75 %)): grasp score increased from 0.5 (0.0; 13.0) to 3.0 (0.0; 15.5) points (р = 0.003) and pinch score increased from 0.5 (0.0; 7.5) to 1.0 (0.0; 12.0) points (р = 0.005) on ARAT scale. In the experimental group, a significant improvement in motor function was found in 33.3 % patients on ARAT scale, and in 30.5 % patients on Fugl-Meyer scale. In the control group, those scores were lower: 9.1 % and 18.2 % patients, respectively.

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