ORIGINAL RESEARCH

Preliminary results of a controlled study of BCI-exoskeleton technology efficacy in patients with poststroke arm paresis

Frolov AA1,2, Mokienko OA1,3, Lyukmanov RKh1,3, Chernikova LA3, Kotov SV4, Turbina LG4, Bobrov PD1,2, Biryukova EV1,2, Kondur AA4, Ivanova GE1, Staritsyn AN1, Bushkova YuV1, Dzhalagoniya IZ2, Kurganskaya ME2,3, Pavlova OG2, Budilin SYu2, Aziatskaya GA3, Khizhnikova AE3, Chervyakov AV3, Lukyanov AL5, Nadareyshvily GG1
About authors

1 Institute of Higher Nervous Activity and Neurophysiology, RAS, Moscow, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

3 Research Center of Neurology, Moscow, Russia

4 Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

5 Municipal Clinical Hospital no. 31, Moscow, Russia

Correspondence should be addressed: Olesya Mokienko
Volokolamskoye shosse, d. 80, kab. 133, Moscow, Russia, 125367; ur.xednay@dm.aysel

About paper

Funding: the study was supported by the Ministry of Education and Science of the Russian Federation (Grant Agreement no. 14.607.21.0128 dated October 27, 2015), Russian Foundation Basic Research grants no. 16-04-01506а and 16-04-00962а.

Received: 2016-03-30 Accepted: 2016-04-07 Published online: 2017-01-05
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The article presents preliminary results of iMove research study. By the time of this publication, the data of 47 patients have been processed. The patients in the experimental group (n = 36) were trained in kinesthetic motor imagery using brain-computer interface (BCI) and a controllable exoskeleton. In the control group, BCI imitation procedures were carried out. In average, the patients had 9 training sessions with a duration of up to 40 minutes. On completing the training, only the experimental group showed improvement in scores (results are presented as median and quartiles (25 %; 75 %)): grasp score increased from 0.5 (0.0; 13.0) to 3.0 (0.0; 15.5) points (р = 0.003) and pinch score increased from 0.5 (0.0; 7.5) to 1.0 (0.0; 12.0) points (р = 0.005) on ARAT scale. In the experimental group, a significant improvement in motor function was found in 33.3 % patients on ARAT scale, and in 30.5 % patients on Fugl-Meyer scale. In the control group, those scores were lower: 9.1 % and 18.2 % patients, respectively.

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