ORIGINAL RESEARCH
Preliminary results of a controlled study of BCI-exoskeleton technology efficacy in patients with poststroke arm paresis
1 Institute of Higher Nervous Activity and Neurophysiology, RAS, Moscow, Russia
2 Pirogov Russian National Research Medical University, Moscow, Russia
3 Research Center of Neurology, Moscow, Russia
4 Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia
5 Municipal Clinical Hospital no. 31, Moscow, Russia
Correspondence should be addressed: Olesya Mokienko
Volokolamskoye shosse, d. 80, kab. 133, Moscow, Russia, 125367; ur.xednay@dm.aysel
Funding: the study was supported by the Ministry of Education and Science of the Russian Federation (Grant Agreement no. 14.607.21.0128 dated October 27, 2015), Russian Foundation Basic Research grants no. 16-04-01506а and 16-04-00962а.
The article presents preliminary results of iMove research study. By the time of this publication, the data of 47 patients have been processed. The patients in the experimental group (n = 36) were trained in kinesthetic motor imagery using brain-computer interface (BCI) and a controllable exoskeleton. In the control group, BCI imitation procedures were carried out. In average, the patients had 9 training sessions with a duration of up to 40 minutes. On completing the training, only the experimental group showed improvement in scores (results are presented as median and quartiles (25 %; 75 %)): grasp score increased from 0.5 (0.0; 13.0) to 3.0 (0.0; 15.5) points (р = 0.003) and pinch score increased from 0.5 (0.0; 7.5) to 1.0 (0.0; 12.0) points (р = 0.005) on ARAT scale. In the experimental group, a significant improvement in motor function was found in 33.3 % patients on ARAT scale, and in 30.5 % patients on Fugl-Meyer scale. In the control group, those scores were lower: 9.1 % and 18.2 % patients, respectively.
Keywords: rehabilitation, brain-computer interface, motor imagery, exoskeleton, paresis, stroke