Funding: the study was performed as a part of the public assignment of the Research Center of Neurology.

Author contribution: Maksimova MYu — concept development and study arrangement, clinical and laboratory data analysis, statistical analysis, manuscript writing; Dubovitskaya YuI — clinical examination of patients, data aquisition and primary analysis of the results; Krotenkova MV — brain MRI, MR venography and neuroimaging diagnosis of cerebral venous sinus thrombosis; Shabalina AA — laboratory analysis of prothrombogenic polymorphic variants of hemostatic and folate metabolism genes.