2020 / 04

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DOI: 10.24075/brsmu.2020.049

ORIGINAL RESEARCH

Hypoxia enhances transcytosis in intestinal enterocytes

Maltseva DV1, Shkurnikov MYu1,2, Nersisyan SA1, Nikulin SV1, Kurnosov AA1, Raigorodskaya MP3, Osipyants AI2,4, Tonevitsky EA5
About authors

1 National Research University Higher School of Economics, Moscow, Russia

2 P. A. Hertsen Moscow Oncology Research Center, branch of the National Medical Research Radiology Center, Moscow, Russia

3 SRC Bioclinicum, Moscow, Russia

4 Far Eastern Federal University, Vladivostok, Russia

5 Fund for Development of Innovative Scientific-Technological Center Mendeleev Valley, Moscow, Russia

Correspondence should be addressed: Diana V. Maltseva
Vavilova, 7, Moscow, 117321; moc.liamg@avestlamd

About paper

Funding: the study was supported by the Ministry of Science and Higher Education of the Russian Federation (Project ID RFMEFI61719X0056).

Acknowledgement: the authors thank the Human Proteome Core Facility (Institute of Biomedical Chemistry) for permission to use the Facility’s equipment.

Author contribution: Maltseva DV — molecular tests, analysis of their results, manuscript preparation; Shkurnikov MYu — analysis of transcriptome and sequencing data, statistical analysis; Nersisyan SA — sequencing data processing, bioinformatic analysis, functional gene analysis; Nikulin SV — cell culture, sample preparation for subsequent proteome analysis, proteomic data analysis; Kurnosov AA — sample preparation for microRNA sequencing, analysis of sequencing data; Raigorodskaya MP — real-time PCR-based analysis of gene expression, transcriptome analysis; Osipyants AI — cell culture, sample preparation for subsequent proteome and transcriptome analyses; Tonevitsky EA — supervision, data analysis, manuscript preparation.

Received: 2020-08-08 Accepted: 2020-08-21 Published online: 2020-08-28
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