ORIGINAL RESEARCH

Taxonomic dysbiosis of gut microbiota and serum biomarkers reflect severity of central nervous system injury

Chernevskaya EA, Meglei AYu, Buyakova IV, Kovaleva NYu, Gorshkov KM, Zakharchenko VE, Beloborodova NV
About authors

Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia

Correspondence should be addressed: Ekaterina A. Chernevskaya
Petrovka, 25, s. 2, Moscow, 127051; ur.rrcknf@ayaksvenrehce

About paper

Compliance with ethical standards: the study was approved by the Ethics Committee of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology (Protocol № 2/19/2 dated June 20, 2019). Informed consent was obtained from all study participants or their legal representatives.

Author contribution: Chernevskaya EA, Meglei AYu — taxonomic microbiota profiling, serum biomarker tests, data analysis, manuscript preparation; Beloborodova NV — study design, final version of the manuscript; Buyakova IV, Kovaleva NYu, Gorshkov KM — patient recruitment and treatment, clinical data collection; ZakharchenkoVE — sample collection, final version of the manuscript. All authors read and approved the final version of the manuscript.

Received: 2020-08-20 Accepted: 2020-09-03 Published online: 2020-09-17
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