ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Neutrophil and monocyte extracellular traps in the diagnosis of post-COVID syndrome
About authors
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Alexander N. Kazimirskii
Ostrovityanov, 1, Moscow, 117997, Russia; ur.liam@01acinla
About paper
Acknowledgements: the authors express their gratitude to all the patients enrolled for their active cooperation and thank the physicians and nurses at the Diagnostic Clinical Center No. 1 of the Moscow Department of Health.
Author contribution: Poryadin GV, Larina VN — study concept and design; Ryzhikh AA, Stodelova EA — data acquisition and processing; Stodelova EA, Kazimirskii AN — experimental studies, preparation of illustrations; Panina MI — statistical data processing; Kazimirskii AN — manuscript writing; Salmasi JM, Panina MI — editing.
Compliance with ethical standards: the study was approved by the Ethics Committee at the Pirogov Russian National Research Medical University (protocol № 203 of 21 December 2021); all patients submitted the informed consent to study participation.
Received: 2022-10-29
Accepted: 2022-11-25
Published online: 2022-12-09
|
Fig. 1. Symptom occurrence in patients with post-COVID syndrome by day 95 [89–109] after the disease onset
Fig. 2. Neutrophil extracellular traps in the form of single DNA filaments emerging from the neutrophil niclei in patients with post-COVID syndrome
Fig. 3. Monocyte extracellular traps in the form of single DNA filaments emerging from the cell niclei in patients with post-COVID syndrome
Table. Laboratory parameters of patients with post-COVID syndrome and healthy donors
Note: Mе — median value; [25–75] — interquartile range.
