ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2022 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Neutrophil and monocyte extracellular traps in the diagnosis of post-COVID syndrome
About authors
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Alexander N. Kazimirskii
Ostrovityanov, 1, Moscow, 117997, Russia; ur.liam@01acinla
About paper
Acknowledgements: the authors express their gratitude to all the patients enrolled for their active cooperation and thank the physicians and nurses at the Diagnostic Clinical Center No. 1 of the Moscow Department of Health.
Author contribution: Poryadin GV, Larina VN — study concept and design; Ryzhikh AA, Stodelova EA — data acquisition and processing; Stodelova EA, Kazimirskii AN — experimental studies, preparation of illustrations; Panina MI — statistical data processing; Kazimirskii AN — manuscript writing; Salmasi JM, Panina MI — editing.
Compliance with ethical standards: the study was approved by the Ethics Committee at the Pirogov Russian National Research Medical University (protocol № 203 of 21 December 2021); all patients submitted the informed consent to study participation.
Received: 2022-10-29
Accepted: 2022-11-25
Published online: 2022-12-09
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Fig. 1. Symptom occurrence in patients with post-COVID syndrome by day 95 [89–109] after the disease onset
Fig. 2. Neutrophil extracellular traps in the form of single DNA filaments emerging from the neutrophil niclei in patients with post-COVID syndrome
Fig. 3. Monocyte extracellular traps in the form of single DNA filaments emerging from the cell niclei in patients with post-COVID syndrome
Table. Laboratory parameters of patients with post-COVID syndrome and healthy donors
Note: Mе — median value; [25–75] — interquartile range.
