ORIGINAL RESEARCH

Neutrophil and monocyte extracellular traps in the diagnosis of post-COVID syndrome

Salmasi JM, Poryadin GV, Panina MI, Larina VN, Ryzhikh AA, Stodelova EA, Kazimirskii AN
About authors

Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Alexander N. Kazimirskii
Ostrovityanov, 1, Moscow, 117997, Russia; ur.liam@01acinla

About paper

Acknowledgements: the authors express their gratitude to all the patients enrolled for their active cooperation and thank the physicians and nurses at the Diagnostic Clinical Center No. 1 of the Moscow Department of Health.

Author contribution: Poryadin GV, Larina VN — study concept and design; Ryzhikh AA, Stodelova EA — data acquisition and processing; Stodelova EA, Kazimirskii AN — experimental studies, preparation of illustrations; Panina MI — statistical data processing; Kazimirskii AN — manuscript writing; Salmasi JM, Panina MI — editing.

Compliance with ethical standards: the study was approved by the Ethics Committee at the Pirogov Russian National Research Medical University (protocol № 203 of 21 December 2021); all patients submitted the informed consent to study participation.

Received: 2022-10-29 Accepted: 2022-11-25 Published online: 2022-12-09
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  1. Yong SJ. Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments. Infect Dis (Lond). 2021; 53 (10): 737–54. DOI: 10.1080/23744235.2021.1924397.
  2. Tirelli U, Taibi R, Chirumbolo S. Post COVID syndrome: a new challenge for medicine. Eur Rev Med Pharmacol Sci. 2021; 25 (12): 4422–5. DOI: 10.26355/eurrev_202106_26154.
  3. Song X, Ji J, Reva B, Joshi H, Calinawan AP, Mazumdar M, Wisnivesky JP, et al. Post-anticoagulant D-dimer is a highly prognostic biomarker of COVID-19 mortality. ERJ open research. 2021; 7 (3): 18. DOI: 10.1183/23120541.00018-2021.
  4. Townsend L, Fogarty H, Dyer A, Martin-Loeches I, Bannan C, Nadarajan P, et al. Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response. J Thromb Haemost. 2021; 19 (4): 1064–70. DOI: 10.1111/jth.15267.
  5. Ostergaard L. SARS CoV-2 related microvascular damage and symptoms during and after COVID-19: Consequences of capillary transit-time changes, tissue hypoxia and inflammation. Physiol Rep. 2021; 9 (3): e14726. DOI: 10.14814/phy2.14726.
  6. Kazimirskii AN, Salmasi JM, Poryadin GV, Panina MI. Novye vozmozhnosti diagnostiki i issledovaniya patogeneza razlichnyx vidov vospaleniya. Patologicheskaya fiziologiya i ehksperimental'naya terapiya. 2022; 66 (2): 34–42. DOI: 10.25557/0031-2991.2022.02.34-42. Russian.
  7. Kazimirskii AN, Salmasi JM, Poryadin GV, Panina MI, Larina VN, Ryzhikh AA. Postkovidnyj sindrom associirovan s povysheniem vnekletochnyx purinovyx osnovanij i nejtrofil'nyx ehkstrakletochnyx lovushek v plazme krovi. Byulleten' sibirskoj mediciny. 2022; 21 (2): 41–47. DOI: 10.20538/1682-03632022-2-41-47. Russian.
  8. Kukes IV, Salmasi JM, Ternovoy KS, Kazimirskii AN, Obodzinskaya TE, Lim VG, i dr. Predposylki k sozdaniyu atlasa postkovidnogo vospaleniya kak sposoba personalizirovannoj farmakoterapii, a takzhe prognozirovaniya i preduprezhdeniya organnyx i sistemnyx disfunkcij. Medicinskij Sovet. 2021; (12): 72–88. DOI: 10.21518/2079-701X-2021-12-72-88. Russian.