Funding: the study was supported by the Russian Science Foundation (RSF), grant № 21-75-00040, https://rscf.ru/en/project/21-75-00040/.

Author contribution: Bakulin IS, Zabirova AH — study planning and design; Bakulin IS, Zabirova AH, Poydasheva AG, Lagoda DYu — experimentation and data acquisition; Bakulin IS, Zabirova AH, Sinitsyn DO — data analysis; all authors — data interpretation; Bakulin IS, Zabirova AH — writing the draft of the manuscript; all authors — manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Research Center of Neurology (protocol № 8-8/21 of 15 September 2021), it was conducted in accordance with the principles of the Declaration of Helsinki. The informed consent was submitted by all study participants.