Funding: the study was funded by the Russian Science Foundation, project № 22-25-00105, https://rscf.ru/project/22-25-00105/.

Author contribution: Guselnikova VV — literature analysis, analysis and interpretation of the results, preparation of the manuscript; Razenkova VA — development of protocols for immunofluorescent reactions, confocal laser microscopy; Sufieva DA — histological examination of biological material, performing immunohistochemical reactions for light microscopy; Korzhevskii DE — concept development, research planning, manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Federal State Budgetary Scientific Institution "IEM" (protocol № 1/22 dated February 18, 2022, protocol № 3/19 dated April 25, 2019), and was conducted in accordance with the provisions of the Declaration of Helsinki (2013)