Acknowledgments: we thank Professor N.E. Kosykh from Far Eastern Medical University for their help in collecting data on the updated incidence of malignant neoplasms in children in Khabarovskij Kraj. We acknowledged Olga P. Gretsova for preparing the data for analysis. S. Venevsky acknowledges the support from the Russian State Assignment of the Federal Research Centre of the Southern Scientific Centre of the Russian Academy of Sciences (SSC RAS) (122013100131-9) and Department of Earth System Sciences of Tsinghua University.

Author contribution: Pinaev SK — author of the general idea and the main design of the study, collection and analysis of data, and formation of hypotheses; Venevsky S — developed method of spatial and non-linear temporal analysis, presentation and interpretation of results of this analysis and made conclusions; Chakov VV — collection and analysis of information about the fire situation in the Far Eastern Federal district on the basis of data presented in the public domain; Linwei Tian — run ARIMA analysis; Chizhov AYa, Peng Gong, Pinaeva OG — participated in the planning of the study and discussion of the results; Kaprin AD, Venevsky S — Participation in research planning and formation of data on CI based on the national cancer registry of Russia; Venevsky S, Pinaev SK — wrote the manuscript.