Funding: the study was supported by the Russian Science Foundation (RSF), grant № 22-25-00078, https://www.rscf.ru/project/22-25-00078/

Author contribution: Suponeva NA, Bakulin IS, Poydasheva AG, Piradov MA — study concept; Suponeva NA, Bakulin IS, Poydasheva AG, Sinitsyn DO, Piradov MA — study planning and design; Bakulin IS, Poydasheva AG, Zabirova AH, Lagoda DYu — research procedure and data acquisition; Bakulin IS, Poydasheva AG, Sinitsyn DO, Zabirova AH — data analysis; all authors — data interpretation; Suponeva NA, Bakulin IS, Poydasheva AG — manuscript draft writing; all authors — manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Research Center of Neurology (protocol 3-7/22 dated 20 April 2022), it was conducted in accordance with the principles of the Declaration of Helsinki; the informed consent was submitted by all study participants.