Funding: the study received financial support from the Russian Science Foundation, project No. 24-15-00032, https://rscf.ru/en/project/24-15-00032/

Author contribution: Razenkova VA — literature analysis, interpretation of the results, manuscript authoring; Kirik OV — analysis of the results, text editing, preparation of figures; Pavlova VS — histology of biological material, immunohistochemical reactions setup; Korzhevskii DE — study conceptualization, planning, text editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Institute of Experimental Medicine (Protocol № 2/24 of April 25, 2024), and conducted in full compliance with the provisions of the Declaration of Helsinki (2013).