Review Assessment Methodology of Rates of Biological Aging in Hygienic Studies (Review)
Kutakova NS, Shushkova TS, Yudina TV
The article presents the analysis of the data of the scientific literature on the use of different methods of assessment of biological age. It is concluded about the validity of the application of this methodology in hygienic studies.
Received: 2013-11-11
Published online: 2017-01-05
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Comments 0
VIEWS 3710
Original research Tuberculosis in Patients with HIV Infection: Epidemiological Situation in the Russian Federation, Detection and Prevention in Modern Conditions
Frolova OP, Novoselova OA, Schukina IV, Stakhanov VA, Kazenniy AB
In order to limit the spread of tuberculosis among HIV-infected patients there have been studied contingents of patients with HIV infection and tuberculosis associated with HIV infection in the Russian Federation as well as the assistance to them on the report form of federal statistical observation No. 61 "Information on the groups of patients with HIV infection" (for 14 years) and the record form "Map of the personal account of the patient with tuberculosis associated with HIV infection" (for 7 years). The research showed that a substantial part of patients with HIV infection (over 30 %) with high-risk of tuberculosis do not pass timely chemoprophylaxis and screening for tuberculosis. Undiagnosed tuberculosis patients are the source of the disease for the population. There are offered measures which could improve coverage of HIV-infected patients with preventive measures and screening examinations for tuberculosis.
Received: 2013-08-28
Published online: 2017-01-05
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VIEWS 3899
Opinion The New in Infectious Diseases Pathogenesis
Uchaykin VF, Shamsheva OV
The clinical picture of an infectious disease, the character of its course, the outcomes depend on the mode of entry. When infection occurs naturally there happens an adequate immune response, the disease manifests typical symptoms, proceeds cyclically and ends with the recovery with formation of a full-fledged sterile immunity. In the case of hematogenous infection these is no full mode of entry and there may develop fulminant forms of the disease or a chronic course with the involvement of visceral organs in the process. Sterilizing immunity is not formed in this case. Complete sanogenesis requires the presence of the pathogen or its mediators in the primary site of infection. HIV, hepatitis C and B, tetanus, rabies should be treated as infectious diseases occurring due to the mechanisms of tropism's change. It provides the emergence of new tropism substrates with subsequent involvement in the process of visceral organs. The challenge for the future is to search for specific mediators of the immune response, triggering and controlling all stages of a germ and macroorganism interaction.
Received: 2013-09-04
Published online: 2017-01-05
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VIEWS 3879
Review The Use of Phytoadaptogens in Oncology (Review)
Chulkova SV, Lyzhenkova MA, Bocharova OA, Egorova AV, Lepkova NV
The article is a review dedicated to one of the most actual aspects of oncology — the use of phytoadaptogens in the therapy of neoplastic diseases. It discloses modern status of the problem as well as underlines most disputable sides of it. The article produces the main properties of phitoadaptogen (antioxidant, antimutagen, antiinflammatory). There is also discussed the ability of the phytoadaptogens to regulate intercellular adhesion and to induce the formation of endogenous interferon.
Received: 2013-06-14
Published online: 2017-01-05
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VIEWS 3739
Original research Possibilities of Ultrasonic Tomography in the Diagnosis of Delineated Liquid Clusters in Patients Operated on for Stomach Cancer
Egorova AV, Chulkova SV, Lepkova NV, Peterson SB, Sholokhov VN, Narimanov MN
The purpose of this study is to assess possibilities of ultrasonic tomography (UST) in the diagnosis of delineated liquid clusters in the patients operated on for stomach cancer. In the study there were analyzed data of 1500 patients operated on for stomach cancer in N.N.BIokhin Russian Cancer Research Center of RAMS for the period from 1998 to 2006. In 221 patients (14.7 %) there were suspected post-operative complications in clinical and laboratory data. 54 patients (3.6 %) were diagnosed with post-operative complications. The latter constituted the main group in our study. Fluid accumulation in the abdominal cavity is formed with equal frequency in all variants of surgical intervention in patients, operated on for stomach cancer. In the diagnosis of abscesses and hematomas UST is characterized by high sensitivity, however, specificity and accuracy of this method does not reach the desired values. The effectiveness of UST and X-ray computed tomography are comparable, X-ray diagnostics has low indicators of sensitivity.  
Received: 2013-06-14
Published online: 2017-01-05
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VIEWS 3735
Review Postoperative Complications of Radical Cystectomy with Ortho- and Heterotopic Intestinal Plasticity (Review)
Darenkov SP, Krivoborodov GG, Kotov SV, Dzitiev VK, Proskokov AA, Pinchuk IS
Radical cystectomy still remains an operative treatment with a significant number of early postoperative complications. This literature review covers the most common postoperative complications of radical cystectomy with intestinal plasticity, such as impaired microcirculation, intestinal paresis, metabolic changes. It is shown the need for further study of the etiology, pathogenesis and the course of postoperative complications. This will develop the optimal strategy for the management of patients after radical cystectomy.
Received: 2013-09-03
Published online: 2017-01-05
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VIEWS 3855
Review The Role of X-Ray and Endoscopic Surgery in the Treatment of Patients with Staghorn Nephrolithiasis in Single or Sole-Functioning Kidney (Review)
Zenkov SS, Nemenova AA, Berestennikov KA, Prityko AA
This article concerns matters of epidemiology, diagnostics and treatment of coral nephrolithiasis. It also touches upon modern classification and the problems of the course of the disease in patients with a single or the only one functioning kidney. The article depicts detailed description of the basic methods of operational treatment as well as the place of percutaneous X-ray and endoscopic surgeries in the treatment of patients with coral nephrolithiasis with a single kidney. Additionally there are reflected complications arising when performing these operations.
Received: 2013-08-28
Published online: 2017-01-05
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VIEWS 3817
Original research Efficiency of Application of Ozone Therapy in Complex Treatment of Iatrogenic Pulpitises
Nikolskaya IA, Kopetskiy IS, Volkov AG, Dikopova NJ, Nosov VV
Currently actively conducted research on the application of various biomaterials and the development of special methods of influence on the tissues allow in complex in the treatment process to influence on the metabolic and regenerative processes in the pulp tissues. Improving the quality of the treatment of reversible pulpitis by application of ozone therapy in combination with the method of direct pulp capping with materials based on calcium hydroxide is aimed at preserving the viability and stimulation of the regenerative function of tooth pulp.
Received: 2013-09-18
Published online: 2017-01-05
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Comments 0
VIEWS 3902